INVITRO STUDIES ON INTERACTION OF MERCURIC MERCURY AND SELENITE IN RABBIT BLOOD

  • 1 January 1978
    • journal article
    • research article
    • Vol. 20  (1) , 139-156
Abstract
The behaviors of inorganic Hg and selenite in rabbit blood, added in vitro individually or in combination, were investigated. Inorganic Hg incorporated into erythrocyte in the absence of selenite was mainly present in the fractions which were eluted from Sephadex G-200 column just after Hb. Se incorporated into erythrocyte in the absence of Hg was eluted in Hb fractions and also in those almost completely retained by the column. In the combination experiment the incorporation of Hb and Se was remarkably enhanced and increased amounts of both compounds were eluted together with each other around the void volume region of the Sephadex G-200 column. The existing state of Hg and Se in high-MW fractions and the effects of some metabolic inhibitors on the behavior of these compounds in blood were also studied.

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