Formiminoglutamicaciduria in Humans with Megaloblastic Anemia: Diminution by Methionine or Glycine.
- 1 February 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 112 (2) , 304-305
- https://doi.org/10.3181/00379727-112-28023
Abstract
Five patients with megaloblastic anemia due to vitamin B12 and/or folic acid deficiency who excreted abnormally large quantities of formimino-glutamic acid (FGA) after a 20 g oral L-histidine HCL load were studied. FGA excretion was markedly reduced in all 4 subjects given 20 g DL-methionine and in both subjects given 20 g glycine together with L-histidine HC1. Of 3 subjects given 20 g DL-serine, 1 showed no reduction in FGA excretion and 2 showed moderate reduction.Keywords
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