Cholesterol Overload Promotes Morphogenesis of a Niemann-Pick C (NPC)-like Compartment Independent of Inhibition of NPC1 or HE1/NPC2 Function
Open Access
- 1 December 2001
- journal article
- Published by Elsevier
- Vol. 276 (49) , 46414-46421
- https://doi.org/10.1074/jbc.m108099200
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Sterol-modulated Glycolipid Sorting Occurs in Niemann-Pick C1 Late EndosomesPublished by Elsevier ,2001
- Identification of HE1 as the Second Gene of Niemann-Pick C DiseaseScience, 2000
- Topological Analysis of Niemann-Pick C1 Protein Reveals That the Membrane Orientation of the Putative Sterol-sensing Domain Is Identical to Those of 3-Hydroxy-3-methylglutaryl-CoA Reductase and Sterol Regulatory Element Binding Protein Cleavage-activating ProteinJournal of Biological Chemistry, 2000
- A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterolBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1999
- The Niemann-Pick C1 Protein Resides in a Vesicular Compartment Linked to Retrograde Transport of Multiple Lysosomal CargoJournal of Biological Chemistry, 1999
- Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol HomeostasisScience, 1997
- Intracellular Trafficking of Cholesterol Monitored with a CyclodextrinJournal of Biological Chemistry, 1996
- Co‐cultivation of Niemann‐Pick disease type C fibroblasts belonging to complementation groupsα andβ stimulates LDL‐derived cholesterol esterificationJournal of Inherited Metabolic Disease, 1996
- Complementation studies in Niemann-Pick disease type C indicate the existence of a second group.Journal of Medical Genetics, 1994
- The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-β-[2-(diethylamino)ethoxy]androst-5-en-17-oneJournal of Biological Chemistry, 1989