Early effects of denervation on isometric and isotonic contractile properties of rat skeletal muscles
- 1 August 1985
- journal article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 124 (4) , 549-555
- https://doi.org/10.1111/j.1748-1716.1985.tb00047.x
Abstract
The contractile properties of the fast-twitch m. extensor digitorum longus (EDL) and the slow-twitch m. soleus were examined after 5 days of denervation. An increase in twitch time to peak, twitch half relaxation time and twitch/tetanus ratio was observed. The EDL also showed a moderate decrease in maximal isotonic shortening velocity, which is taken as an indication that the contractile proteins are affected. A fatigue test showed that the EDL became less fatigable and the soleus less fatigue resistant after denervation.Keywords
This publication has 18 references indexed in Scilit:
- Firing patterns of motor units in normal ratsNature, 1985
- Non‐Hyperbolic Force‐Velocity Relationship in Single Muscle Fibres1Acta Physiologica Scandinavica, 1976
- Significance of impulse activity in the transformation of skeletal muscle typeNature, 1976
- Contractile properties of muscle: control by pattern of muscle activity in the ratProceedings of the Royal Society of London. B. Biological Sciences, 1974
- Contraction properties and ATPase activity in fast and slow muscle of the rat during denervationExperimental Neurology, 1972
- The effect of denervation on the mechanical and electrical responses of fast and slow mammalian twitch muscleThe Journal of Physiology, 1972
- Effect of denervation on fragmented sarcoplasmic reticulum of white and red muscleExperimental Neurology, 1970
- Caffeine-induced contracture and potentiation of contraction in normal and denervated rat muscleLife Sciences, 1965
- Dynamic properties of fast and slow skeletal muscles of the rat during developmentThe Journal of Physiology, 1964
- The heat of shortening and the dynamic constants of muscleProceedings of the Royal Society of London. B. Biological Sciences, 1938