Solvent effect and NMR behaviour in a chiral amidophosphine mediated reaction of organocuprate with chalcone

1 January 1993

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 16,p. 1248-1249
https://doi.org/10.1039/c39930001248

Abstract

A dramatic reversal in the direction of enantiofacial differentiation has been observed in a chiral phosphine mediated reaction of organocuprate with chalcone providing S- and R-products in diethyl ether and tetrahydrofuran (THF), respectively, and correlated with the pattern of coordination.

Keywords

SOLVENT EFFECT