Abstract
The histochemical enzyme activity of alkaline phosphatase, nonspecific esterase, 5-nucleotidase, .beta.-glucuronidase, glucose-6-phosphatase, succinate dehydrogenase and glucose-6-phosphate dehydrogenase in human bladder cancer was investigated. Tumors of 84 patients, classified into grades I-III according to the WHO classification, were compared with 12 normal and 16 inflamed bladder epithelia. Loss of alkaline phosphatase activity and a decrease of nonspecific esterase activity was found in most tumors. The activity of .beta.-glucuronidase was decreased and compared with normal tissue, as was the activity of 5-nucleotidase. The succinate dehydrogenase activity in tumor tissue was frequently increased; glucose-6-phosphate dehydrogenase did not show any significant reaction.

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