2'-5' Oligo(A) Synthetase Levels in Interferon-sensitive or -resistant Lymphoid Cells

Abstract
The activity of 2''-5'' oligo(A) synthetase was measured in control and interferon-treated lymphoid cells. While control or interferon-treated Raji and Namalwa cells exhibit low activity of the 2''-5'' oligo(A) synthetase, the activity of this enzyme is increased 20-fold when Daudi cells are treated with the same dose of human interferon. The same enzyme is induced by interferon in P3HR-1 cells to a lesser extent.

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