Constructing a Golgi complex
Open Access
- 10 December 2001
- journal article
- editorial
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 155 (6) , 873-876
- https://doi.org/10.1083/jcb.200109095
Abstract
In this issue, Short et al. report the discovery of a protein named Golgin-45 that is located on the surface of the middle (or medial) cisternae of the Golgi complex. Depletion of this protein disrupts the Golgi complex and leads to the return of a resident, lumenal, medial Golgi enzyme to the endoplasmic reticulum. These findings suggest that Golgin-45 serves as a linchpin for the maintenance of Golgi complex structure, and offer hints as to the mechanisms by which the polarized Golgi complex is constructed.Keywords
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