Response to autoimmune enteropathy to cyclosporin A therapy.
Open Access
- 1 November 1991
- Vol. 32 (11) , 1421-1425
- https://doi.org/10.1136/gut.32.11.1421
Abstract
Small bowel enteropathies that are associated with an autoimmune process are often resistant to treatment. Two children with autoimmune enteropathy were treated with cyclosporin A for eight months. Both improved, as assessed by growth, small intestinal mucosal morphology, and carbohydrate absorption. Cyclosporin A is useful in the treatment of autoimmune enteropathy. This report also suggests that T cell activation (which is suppressed by cyclosporin A) is important in the pathogenesis of this condition.Keywords
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