Human pancreatic amylase polymorphism: Formal genetics and population genetics
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 51 (2) , 217-220
- https://doi.org/10.1007/bf00287179
Abstract
The genetically determined polymorphism of human pancreatic amylase (E.C. 3.2.1.1), AMY2, is demonstrated in serum specimens by agarose gel electrophoresis. We, investigated 325 mother-child pairs and 2594 unrelated individuals from southwestern Germany. This study confirms the formal hypothesis of two common alleles AMY 2 1 , AMY 2 2 and possibly two rare alleles AMY 2 3 , AMY 2 4 at an autosomal locus AMY2. The frequency of the AMY 2 1 allele, was calculated as 0.951; AMY 2 3 and AMY 2 4 seem to have a frequency of 0.001 in this sample.Keywords
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