Spontaneous Shrinking of Human Red Cell Ghosts

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Abstract
Some of the ghosts made by exposing human red cells to hypotonic media undergo a slow contraction to form small spherical bodies to which clusters of myelin forms are attached. These bodies have a volume of 4 - 17% of the volume of the intact red cell, and it is probable that they represent the "fixed framework" of the red cell, reduced to a compact spherical mass. If so, the thickness of the wet surface ultrastructure of the ghost would lie between 250 A and 1000 A.

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