An Enzyme-linked Immunosorbent Assay (ELISA) for PBS Z1, a Defective Phage of Bacillus subtilis

Abstract
The sensitivity, reproducibility and specificity of an enzyme-linked immunosorbent assay (ELISA) for the defective phage PBS Z1 of B. subtilis were investigated. Phages in concentrations between 108 and 2.5 .times. 1010 particles/ml could be assayed with this method. The coefficient of variation for concentrations between 5 .times. 108-5 .times. 109 particles/ml was about 10%. From other Bacillus phages tested, only the defective phages resembling PBS Z1 in morphology were detected efficiently with the ELISA for PBS Z1. ELISA is compared to other assays for PBS Z1.

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