Cerebral Blood Flow During Convulsions
- 1 April 1969
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 20 (4) , 396-405
- https://doi.org/10.1001/archneur.1969.00480100072011
Abstract
EARLIER studies1on unanesthetized rats have shown that the toxic action of O2at high pressure (OHP) on the central nervous system has been associated with cyclic synchronous and asynchronous changes in the O2availability in localized regions of the brain. The nature of these regional PO2changes suggest they might possibly be due to or associated with regional changes in cerebral blood flow (CBF). The present experiments were carried out in an attempt to get further and more direct evidence concerning such changes in CBF in the rat. The heated thermocouple technique, a refinement of the method used in earlier blood flow studies2has been used for continuously recording any regional changes in blood flow from chronically implanted flow sensors. Various modifications of this method originally designed by Gibbs3,4to investigate the blood flow in the internal jugular vein of man wereKeywords
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