THE DIAGNOSTIC VALUE OF BLOOD FIBRIN DETERMINATIONS

Publisher Website
Google Scholar
Abstract
Fibrin, in marked contrast to the other proteins of the blood, varies widely in amount. Persons may differ as to the fibrin content of their blood, but for the same person in health the amount is always essentially the same. On the other hand, in disease, according to the nature of the morbid process, fibrin values vary to a marked degree. This very labile blood protein is found only in the plasma—not in the cells. Its source has been variously stated by investigators to be the intestinal wall, the bone marrow, or the liver. Whipple has demonstrated in animals that the production of fibrin is stimulated by slight liver injury, while it is depressed by extensive injury. He has reason to believe that this protein is being constantly used up in the body, and his experiments point to the liver as the sole source of supply. One is tempted, therefore,

This publication has 0 references indexed in Scilit: