Abnormal Myoglobin Ultraviolet Spectrum in Duchenne Type of Progressive Muscular Dystrophy

25 October 1963

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 142 (3591) , 490-491
https://doi.org/10.1126/science.142.3591.490

Abstract

Met-myoglobin isolated from gluteal muscle of cases with Duchenne type of progressive muscular dystrophy showed an abnormal ultraviolet spectrum. The maximum of the spectrum at pH 7.0 was at 275 mµ, in contrast to that at 281 m/ A in normal met-myoglobin. Such an abnormality was not found in the limb-girdle type of dystrophy and in progressive spinal muscular atrophy. The results indicate the presence of an abnormal myoglobin in the Duchenne type of progressive muscular dystrophy.

Keywords

This publication has 2 references indexed in Scilit:

Abnormal Spectrophotometric Absorption Spectrums of Myoglobin in Two Forms of Progressive Muscular Dystrophy
New England Journal of Medicine, 1961
Studies on Human Myoglobin
Blood, 1955