Abstract
Much work is being done on the respiratory metabolism of central and peripheral nerve tissue. Ashford,1Dickens and Greville,2Holmes,3Himwich and his co-workers,4Peters and Sinclair,5Quastel and Wheatley,6Wortis7and others have recently reported such studies. It has been the aim of most workers in this field (1) to determine the nature of the foodstuffs utilized by various animal tissues and (2) to measure, when possible, the ability or limitation of ability of nerve tissue to continue such normal oxidation of foodstuffs under the influence of disease or drugs. METHODS Experimental approach to these problems has been accomplished mainly by two technical methods: The first one is the Barcroft-Warburg method,8wherein small amounts of accurately weighed living tissue are kept under nearly physiologic conditions and the gaseous metabolism (i. e., the oxygen consumption and carbon dioxide production) is accurately measured.

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