Dexamethasone treatment of brain tumor patients
- 1 November 1985
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 35 (11) , 1610
- https://doi.org/10.1212/wnl.35.11.1610
Abstract
Regional values for cerebral blood flow, blood volume, oxygen extraction fraction, and oxygen utilization were measured, using PET, in 10 brain tumor patients before and after treatment with dexamethasone. Dexamethasone treatment decreased cerebral blood flow and blood volume and increased the fractional extraction of oxygen throughout the brain without affecting oxygen utilization. Dexamethasone probably causes direct vasoconstriction of cerebral blood vessels.Keywords
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