Allergenic nature of Parthenium hysterophorus

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Abstract
Parthenin has been reported as the active allergen in P. hysterophorus contact sensitivity. A study was carried out to test various chemical fractions of the plant for isolating and identifying the exact allergens. Two additional sesquiterpene lactones apart from parthenin were allergenically active. Structures of these sesquiterpenoids are presented. Photopatch tests [on humans] do not indicate a photosensitizing capacity for these compounds.