AMNIOTIC FLUID REACTIVITY DETECTED BY SOMATOMEDIN C RADIORECEPTOR ASSAY: CORRELATION WITH GROWTH HORMONE, PROLACTIN AND FETAL RENAL MATURATION
- 1 May 1976
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 42 (5) , 983-986
- https://doi.org/10.1210/jcem-42-5-983
Abstract
Amniotic fluid was assayed by a radioreceptor assay utilizing 125I-somatomedin C and placental membranes. Growth hormone and prolactin levels were measured by radioimmunoassay at different gestational ages (8-41 weeks). Somatomedin receptor activity, growth hormone, and prolactin reached high levels during early gestation (8-26 weeks) displaying different patterns of appearance which reflect fetal serum levels of these hormones. After 26 weeks gestation all these hormones decreased in concentration. This decrease showed a strong correlation with fetal renal maturation as measured by amniotic fluid creatinine levels.Keywords
This publication has 1 reference indexed in Scilit:
- Studies on Human Sexual Development. III. Fetal Pituitary and Serum, and Amniotic Fluid Concentrations of LH, CG, and FSHJournal of Clinical Endocrinology & Metabolism, 1976