Abstract
The process of homogeneous nucleation and grain growth is formulated, where the chemical reaction accompanying nucleation and growth is taken into account under the assumption that the rates of nucleation and grain growth are determined by one key molecular species. This theory is applied to the condensation of refractory minerals in a cooling gas of the solar composition. Condensation sequence of refractory minerals and their grain size are presented as a function of the cooling time of gas and the total gas pressure. The formation of refractory grains in sites of astrophysical interest is discussed.

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