Phagocytosis and Intracellular Fate of Sporothrix schenckii

1 December 1979

journal article
research article
Published by Oxford University Press (OUP) in The Journal of Infectious Diseases

Vol. 140 (5) , 815-817
https://doi.org/10.1093/infdis/140.5.815

Abstract

Human polymorphonuclear leukocytes (PMNLs) phagocytized and killed yeast-phase cells of Sporothrix schenckii in vitro in the presence of 10% unheated serum. The combination of H₂O₂, KI, and human PMNL myeloperoxidase was lethal to yeast-phase S. schenckii. The results of this investigation suggest that PMNLs may play an important role in host resistance to infection with S. schenckii.

Keywords

PHAGOCYTOSIS
SPOROTHRIX SCHENCKII
YEASTS
INFECTION
HYDROGEN PEROXIDE
NEUTROPHIL
PEROXIDASE
HOST (ORGANISM)

This publication has 1 reference indexed in Scilit:

Role of the Phagocyte in Host-Parasite Interactions XII. Hydrogen Peroxide-Myeloperoxidase Bactericidal System in the Phagocyte
Journal of Bacteriology, 1967