Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1): A Potential Prognostic Marker Involved in Leukocyte Infiltration of Renal Cell Carcinoma
- 1 January 1996
- journal article
- research article
- Published by S. Karger AG in Oncology
- Vol. 53 (2) , 127-132
- https://doi.org/10.1159/000227548
Abstract
We investigated immunohistochemically the leukocyte infiltrate [CD3, CD4, CD8, CD11a, CD11b, CD14, CD56, VLA-4 and platelet endothelial cell adhesion molecule-1 (PECAM-1)] and the endothelial expression of cell adhesion molecules (PECAM-1, VCAM-1, ICAM-1 and ICAM-2) in 23 renal cell carcinoma tumor tissues. Tumors with a moderate or high density of PECAM-1-positive endothelia showed a stronger infiltration with PECAM-1-positive leukocytes as compared to tumors with a low density of positive endothelia (pKeywords
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