Rapid and simple determination of selenium and other trace elements in very small blood samples by XRF
- 1 June 1988
- journal article
- Published by Springer Nature in Biological Trace Element Research
- Vol. 16 (1) , 87-95
- https://doi.org/10.1007/bf02795337
Abstract
Selenium and other trace elements (Cu, Zn, Br, and Rb) were determined in very small (0.75 μL) human serum and mice whole blood samples, by an XRF method. Accurate results of elemental concentration were obtained without the need of exact volume measurement, because of the backscatter correction used. The XRF method is highly sensitive (M.D.L.=0.06, 0.13, 0.09, 0.07, and 0.05 ppm for Se, Cu, Zn, Br, and Rb, respectively), rapid (counting time—100 s/sample), easy to perform and therefore suitable for routine trace element analyses. The results obtained are in good agreement with the values reported in the literature.Keywords
This publication has 14 references indexed in Scilit:
- Trace element determination using synchrotron radiationAnalytical Chemistry, 1986
- Energy dispersive x-ray fluorescence spectrometry with direct excitation at picogram levelsAnalytical Chemistry, 1985
- Selenium in carcinogenesisBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1984
- Selenium and vitamin E in relation to risk factors for coronary heart disease.Journal of Clinical Pathology, 1984
- Elevated Serum Selenium in Diabetic ChildrenActa Paediatrica, 1984
- Determination of trace elements in human serum by energy dispersive X-ray fluorescenceClinical Biochemistry, 1981
- Bestimmung von Fe, Co, Cu, Zn, Se, Rb und Cs in NBS-Ochsenleber, Blutplasma und Erythrocyten durch INAA und AASAnalytical and Bioanalytical Chemistry, 1981
- Determination of selenium in the environment and in biological material.Environmental Health Perspectives, 1981
- X-ray fluorescence determination of trace selenium in organic and biological matricesAnalytical Chemistry, 1980
- Cancer mortality correlation studies-III: Statistical associations with dietary selenium intakesBioinorganic Chemistry, 1977