Human mast cells take up and hydrolyze anandamide under the control of 5‐lipoxygenase and do not express cannabinoid receptors
Open Access
- 22 February 2000
- journal article
- Published by Wiley in FEBS Letters
- Vol. 468 (2-3) , 176-180
- https://doi.org/10.1016/s0014-5793(00)01223-0
Abstract
Human mast cells (HMC‐1) take up anandamide (arachidonoyl‐ethanolamide, AEA) with a saturable process (K m=200±20 nM, V max=25±3 pmol min−1 mg protein−1), enhanced two‐fold over control by nitric oxi...Keywords
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