Abstract
SUMMARY: A computer simulation of the genetic analysis of the asexual life cycle ofPhycomyces' heterokaryons has been carried out. We have studied experimentally the relationship between the nuclear proportion in heterokaryotic mycelia containing prototrophic and auxotrophic nuclei and their growth rates. We discuss possible evolutionary implications of heterokaryosis in coenocytic fungi and the genetic applications of the quantitative complementation technique.

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