Plasma lipid peroxides and alpha-tocopherol in critically ill patients
- 1 November 1984
- journal article
- research article
- Published by Wolters Kluwer Health in Critical Care Medicine
- Vol. 12 (11) , 957-959
- https://doi.org/10.1097/00003246-198411000-00007
Abstract
Plasma lipid peroxide measured as thiobarbituric acid reactive substances (TBARS) and alpha-tocopherol levels in 24 critically ill patients were compared with those of control subjects. The mean plasma alphatocopherol level was significantly lower and the mean TBARS level was significantly higher in critically ill patients. Eight ICU patients developed disseminated intravascular coagulation (DIC); the mean TBARS level during DIC was significantly above the mean pre-DIC level. These results indicate that lipid peroxidation may contribute to the development of DIC in critically ill patients.Keywords
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