A possible role of rabbit heart cytosol tocopherol binding in the transfer of tocopherol into nuclei

15 August 1980

journal article
research article
Published by Portland Press Ltd. in Biochemical Journal

Vol. 190 (2) , 469-471
https://doi.org/10.1042/bj1900469

Abstract

An alpha-tocopherol-binding macromolecule was isolated from the heart cytosol of rabbits fed for 1 month with an alpha-tocopherol-deficient diet. The amount of [3H]-tocopherol bound to nuclear chromatin was increased when the alpha-tocopherol-deficient heart nuclei were incubated in the presence of [3H]tocopherol-cytosol complex. In this condition, large amounts of [3H]tocopherol were associated with a subnuclear fraction that contained non-histone acidic proteins.

This publication has 13 references indexed in Scilit:

Effect of α-tocopherol on hypoxic-perfused and reoxygenated rabbit heart muscle
Journal of Molecular and Cellular Cardiology, 1978
Biochemical mechanisms accounting for the toxic action of oxygen on living organisms: The key role of superoxide dismutase
Cell Biology International Reports, 1978
Rat liver α-tocopherol binding protein
Biochimica et Biophysica Acta (BBA) - General Subjects, 1977
Production of superoxide anions and hydrogen peroxide in Ehrlich ascites tumour cell nuclei
Biochimica et Biophysica Acta (BBA) - General Subjects, 1977
Studies on the binding of d-α-tocopherol to rat liver nuclei
Archives of Biochemistry and Biophysics, 1977
An α-tocopherol binding protein in rat liver cytoplasm
Biochemical and Biophysical Research Communications, 1975
Effects of extracts of rat tissues on the action of bleomycin
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975
Polyamine and nucleoprotein correlations in hypertrophied and perfused heart.
1975
DECREASE OF MELTING TEMPERATURE AND SINGLE STRAND SCISSION OF DNA BY BLEOMYCIN IN THE PRESENCE OF HYDROGEN PEROXIDE
The Journal of Antibiotics, 1969
A RELATIONSHIP OF VITAMIN E TO NUCLEIC ACID METABOLISM
Journal of Biological Chemistry, 1951