Direct Optical Resolution of Carboxylic Acids by Chiral HPLC on Tris(3,5-dimethylphenylcarbamate)s of Cellulose and Amylose
- 5 July 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 17 (7) , 1125-1128
- https://doi.org/10.1246/cl.1988.1125
Abstract
A variety of racemic carboxylic acids have been for the first time directly resolved by normal-phase, high-performance liquid chromatography using a hexane-2-propanol eluting system containing a small amount (≈1%) of a strong carboxylic acid, like formic acid, trichloroacetic acid, and trifluoroacetic acid.Keywords
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