Peripheral nerve concentrations of glucose, fructose, sorbitol and myoinositol in diabetic and non-diabetic patients
- 1 July 1987
- journal article
- research article
- Published by Springer Nature in Diabetologia
- Vol. 30 (7) , 464-467
- https://doi.org/10.1007/bf00279613
Abstract
Glucose, fructose, sorbitol and myoinositol concentrations were measured in biopsies of peripheral nerve obtained at above-knee or below-knee amputation. In diabetic patients nerve glucose (median [range]) (5.09 [1.62–12.82] vs 3.12 [1.81–4.01]) ppp<0.02, μmol/g wet weight) were significantly higher than in non-diabetic patients. No significant difference was found in myoinositol concentration (1.95 [1.00–3.55] vs 2.09 [1.27–5.40] μmol/g wet weight). Concentrations differed markedly from previously reported values in human nerve obtained at post-mortem.This publication has 17 references indexed in Scilit:
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