Laboratory investigations of dermatophyte infections of nails

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Abstract
Analysis of the results of repeated investigations of a series of nail infections gives support for the view that the major reason for difficulty in culturing dermatophytes from microscopically positive nails is the presence of non-viable hyphae in the distal portion of the nail accessible to sampling. The results also indicate that griseofulvin treatment because of its effect on the fungus-keratin relationship probably improves the cultural result.

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