Practice Imperfect — Treatment for Wheezing in Preschoolers

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Abstract
Nearly one third of preschool children (4 years of age or younger) have intermittent wheezing, a condition that many of them outgrow. The most common early trigger is a respiratory virus infection, leading to a pattern of episodic wheezing, with no symptoms between viral infections. Some children, particularly those with atopy, have a different clinical phenotype known as “multitrigger” wheezing. This condition is characterized by wheezing after exposure to multiple triggers, such as exercise and exposure to smoke, allergens, or cold air, as well as viral infections.1 The distinctions among types of wheezing are not fixed. For example, an 18-month-old . . .