A Possibility of Unbiased Sex Preselection in Humans by Enrichment of X or Y Chromosome Bearing Spermatozoa

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Abstract
Human sex ratio is generally 1.06. The motility selected population of spermatozoa are usually Y chromosome rich. It is therefore easier to influence selected male births. Social and pscyhologic factors and economic needs intensified by high technology may cause further imbalance in the sex-ratio, creating a demand for techniques to influence sex selection. Such techniques may also help to handle sex linked defects. An examination of severe studies on the sex chromosome distribution of human spermatozoa, based on HOP method, showed a preponderance of either X or Y bearing male pronuclei, depending on certain experiment conditions, indicating a technical possibility of influencing sex in the unbiased way.