Abnormal elimination reactions of 3β,17β-diacetoxy-5β,6β-epoxyandrostan-7β-ol
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 3,p. 263-267
- https://doi.org/10.1039/p19780000263
Abstract
Reaction of 3β,17β-diacetoxy-5β,6β-epoxyandrostan-7β-ol with phosphorus oxychloride affords 3β,17β-diacetoxyandrost-5-en-7-one whilst with methanesulphonyl chloride–sulphur dioxide it gives 17β-acetoxy-3β-methylsulphonyloxyandrost-5-en-7-one. Normal products are obtained with the epimeric 5α,6α-epoxy-7α-ols and in the absence of a 3β-substituent.This publication has 0 references indexed in Scilit: