RELATION BETWEEN RNA, DNA, AND PROTEIN SYNTHESES IN THE REPLICATING NUCLEUS OF EUPLOTES

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Abstract
Localization and synthesis of RNA, DNA, and protein have been studied in the replicating nucleus of Euplotes. At the reorganization band, DNA undergoes in succession two marked changes in organization. DNA shifts from a granular state to a dispersed form and finally becomes very dilute; at the time the latter condition is reached, DNA synthesis takes place. Histidine incorporation is heavy only in the region of DNA synthesis. RNA is essentially completely destroyed or eliminated from the nucleus just ahead of the advancing wave of DNA synthesis. Neither RNA synthesis nor RNA are detectable in the zone of DNA synthesis.