The metabolic effects of hemodialysis with and without glucose in the dialysate
Open Access
- 1 October 1978
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 31 (10) , 1870-1875
- https://doi.org/10.1093/ajcn/31.10.1870
Abstract
The present study compares some of the metabolic effects of hemodialysis of fasting patients with and without glucose in the dialysate bath. Unlike glucose dialysis, glucose-free dialysis caused marked decreases in blood levels of glucose, insulin, lactate, and pyruvate along with profound increases in acetoacetate and β-hydroxybutyrate. It is concluded that oxidation of fatty acids increases to meet energy demands and that the combined processes of glycogenolysis and gluconeogenesis serve to prevent critical hypoglycemia during glucose-free dialysis.Keywords
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