Platelets and Platelet Function in Patients with Chronic Uremia on Maintenance Hemodialysis
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in Nephron
- Vol. 23 (5) , 233-236
- https://doi.org/10.1159/000181641
Abstract
In 20 chronic uremic patients on maintenance hemodialysis, who were not taking any medication known to affect platelet function, the following investigations were carried out: platelet count, fibrin/fibrinogen degradation products, fibrinogen and plasminogen concentration, platelet adhesiveness, clot retraction and platelet aggregation induced by ADP, ristocetin, fibrinogen, collagen and epinephrine. The only significant abnormal result was a decreased clot retraction. We consider many cases of so-called uremic bleeding to be caused by the medication taken and conclude that on well-controlled hemodialysis treatment, bleeding tendency should not be a major problem.Keywords
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