Is leukocytosis a predictor of mortality in severe pertussis infection?
- 1 October 2000
- journal article
- neonatal and-pediatric-intensive-care
- Published by Springer Nature in Intensive Care Medicine
- Vol. 26 (10) , 1512-1514
- https://doi.org/10.1007/s001340000587
Abstract
Bordetella pertussis causing severe respiratory failure in infants that is unresponsive to treatment is well described. Pulmonary hypertension is a prominent feature of such cases. In this series of 13 critically ill infants with B. pertussis, hyperleukocytosis (>100×109/l) was an independent predictor of death. We suggest that such extreme leukocytosis may contribute to disease severity via the formation of aggregates in the pulmonary vasculature.Keywords
This publication has 0 references indexed in Scilit: