Tumors Associated With Embedded Polymers2
- 1 August 1959
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 23 (2) , 305-315
- https://doi.org/10.1093/jnci/23.2.305
Abstract
A study was made of the long-term tissue effects of certain polymers when embedded in the subcutaneous tissues of the abdominal wall of rats. Five of the 299 animals that survived 300 days or more developed malignant tumors at the site of the implants. The tumors included 4 spindle-cell sarcomas and 1 undifferentiated sarcoma. A benign fibroma was found about one implant.Keywords
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