Starvation effect on rat kidney peroxisomal and microsomal fatty acid oxidation
- 3 May 1993
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 322 (1) , 61-64
- https://doi.org/10.1016/0014-5793(93)81111-c
Abstract
Microsomal lauric acid 12-hydroxy lauric acid (ω)-hydroxylation and fatty acid peroxisomal β-oxidation were studied in kidney tissue from starved rats. Starvation increased the microsomal ω-hydroxylation and peroxisomal β-oxidation of fatty acids with a high correlation between both processes. Earlier, we reported similar results in liver. Our results support the hypothesis that the role of microsomal fatty acids ω-hydroxylation is the generation of substrate for peroxisomal β-oxidation, with the final purpose of contributing to a catabolic or gluconeogenic pathway from fatty acids.Keywords
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