Path of the polypeptide in bacteriorhodopsin.
- 1 April 1980
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 77 (4) , 2023-2027
- https://doi.org/10.1073/pnas.77.4.2023
Abstract
An attempt was made to fit the amino acid sequence of [Halobacterium halobium] bacteriorhodopsin to the 3-dimensional density map of the molecule. First, 7 segments of the sequence were selected as being probable transmembrane .alpha. helices. Then each of the 5040 possible ways of fitting these 7 segments into the 7 regions of helical density in the map were evaluated based on the criteria of connectivity of the nonhelical link regions, charge neutralization, and total scattering density per helix. A single model that may be experimentally tested emerged as the most probable.This publication has 12 references indexed in Scilit:
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