Comparison of a DNA probe assay with culture for the detection of Chlamydia trachomatis
Open Access
- 1 September 1991
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 35 (3) , 159-161
- https://doi.org/10.1099/00222615-35-3-159
Abstract
A new DNA probe assay (PACE 2, Gen-probe) was compared with cell culture for the detection of Chlamydia trachomatis in 909 women attending the Royal Women's Hospital, Melbourne, Victoria. The DNA probe assay had a sensitivity of 86.2%, a specificity of 99.9% and a positive predictive value of 96.2% in a population with 3.2% prevalence, indicating that it may be a suitable alternative to culture for the detection of C. trachomatis in specimens from the genital tract.Keywords
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