Antiinflammatory Drugs and Gastrointestinal Bleeding: A Comparison of Aspirin and Ibuprofen
- 9 August 1976
- journal article
- research article
- Published by Wiley in The Journal of Clinical Pharmacology
- Vol. 16 (8-9) , 418-425
- https://doi.org/10.1002/j.1552-4604.1976.tb02416.x
Abstract
Gastrointestinal blood loss provoked by short-term and long-term therapy with aspirin and ibuprofen was compared in patients with rheumatoid arthritis. Blood loss was assessed by isotope counting of 4-day stool collections after infusion of 51Cr-labeled autologous erythrocytes. After 2 wk on drug or after 1 yr on drug, aspirin consistently caused more bleeding than ibuprofen.This publication has 10 references indexed in Scilit:
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