Effect of RANTES on Intracellular Expression of EG2 Antigen in Eosinophils
- 1 January 1995
- journal article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 108 (1) , 43-44
- https://doi.org/10.1159/000237200
Abstract
RANTES, which is released from thrombin-stimulated platelets, is a member of the 8-kDa cytokine family that has been shown to possess chemotactic activity for eosinophils. The effect of RANTES on the intracellular expression of EG2 antigen in eosinophils was examined in this study. RANTES augmented the intracellular expression of EG2 antigen in eosinophils. These findings suggest that RANTES not only modulates the chemotactic activity of eosinophils but also intensifies the function of eosinophil activation.Keywords
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