Isolation of rat mammary epithelial cells for polyamine analysis

Abstract
Mammary epithelial cells were isolated from either abdominal-inguinal glands or mammary tumors of rats, after enzymic digestion of the tissues, and were analyzed for polyamine content. Optimum conditions were developed for the isolation of cells in sufficient yield for the analysis of polyamines from 1 g of mammary gland or 0.5 g of tumor tissue. Complete recoveries of the polyamines in the tissues were achieved in the isolated epithelial cells.