Effects of hypophysectomy and of LH administration on luteal phase plasma progesterone levels in the beagle bitch

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Abstract
Luteal-phase progesterone levels in 5 beagle bitches fell to 0.3-0.4 ng/ml within 3-17 days after hypophysectomies on day 10-50 of the cycle. Plasma progesterone in 6 bitches increased (P < 0.01) within 3 h after luteinizing hormone [LH] (100 .mu.g/kg) injection from days 35-55 of the cycle. Normal luteal function in the bitch appears to require continuous pituitary trophic support perhaps involving LH.

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