Progress and Rate of Absorption of Radiostrontium Through Intestinal Tracts of Rats.

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Abstract
Rate of absorption of Sr89 from ligated loops of rat intestine, and rate of passage of Sr89 through the intact intestinal tract were measured. Assuming only that absorption rate in ligated loops is reasonably the same as rate of absorption from that segment in the intact rat, the actual effective absorption was estimated. The highest initial rate of absorption occurred in the duodenum with jejunum, ileum, colon and stomach following in decreasing order. Since the radiostrontium passed rapidly through the duodenum and jejunum, the largest actual effective absorption occurred in the ileum (65%), with smaller contributions by the jejunum (17%), colon (8%), duodenum (7%), and stomach (2%). Two factors were found to limit Sr89 absorption: (1) Movement of the isotope into gut segments having slower absorption rate, and (2) decreased absorption of Sr89 in each gut loop with time.