Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
Top Cited Papers
Open Access
- 19 March 2004
- journal article
- research article
- Published by Elsevier
- Vol. 116 (6) , 855-867
- https://doi.org/10.1016/s0092-8674(04)00215-6
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Crystal structure of an activated Akt/Protein Kinase B ternary complex with GSK3-peptide and AMP-PNPNature Structural & Molecular Biology, 2002
- RAF/RAS oncogenes and mismatch-repair statusNature, 2002
- Mutations of the BRAF gene in human cancerNature, 2002
- Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogsLeukemia, 2002
- Ras Activation of the Raf Kinase: Tyrosine Kinase Recruitment of the MAP Kinase CascadeRecent Progress in Hormone Research, 2001
- Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsBiochemical Journal, 2000
- Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine KinaseScience, 2000
- Kinetic Analyses of Mutations in the Glycine-Rich Loop of cAMP-Dependent Protein KinaseBiochemistry, 1998
- Oligomerization activates c-Raf-1 through a Ras-dependent mechanismNature, 1996
- Improved methods for building protein models in electron density maps and the location of errors in these modelsActa Crystallographica Section A Foundations of Crystallography, 1991