Activation of Hageman Factor by L-Homocystine
- 29 November 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 162 (3857) , 1007-1009
- https://doi.org/10.1126/science.162.3857.1007.b
Abstract
L-Homocystine activates Hageman factor, as demonstrated by its capacity to initiate clotting and to induce the evolution of plasma kinins. Perhaps, strategically located deposits of this amino acid are responsible for the unusual frequency of thrombosis in patients with homocystinuria.Keywords
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