RNA-dependent DNA polymerase activity of RNA tumor virus. VI. Processive mode of action of avian myeloblastosis virus polymerase
- 1 September 1976
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 19 (3) , 932-939
- https://doi.org/10.1128/jvi.19.3.932-939.1976
Abstract
Purified avian myeloblastosis virus (AMV) polymerase consisting of .alpha.,.beta. subunits acted processively in catalyzing DNA synthesis primed with 34S AMV RNA.cntdot.oligo(dT), poly(A).cntdot.poly(dT) and poly(I).cntdot.poly(dC). DNA transcripts prepared with 34S AMV RNA.cntdot.oligo(dT)14 and AMV polymerase (.alpha..beta.) had a MW of 1.05 .times. 106, or approximately 1/3 the size of the 34S RNA genome. Polymerase subunit .alpha. acts nonprocessively with the above templates.This publication has 31 references indexed in Scilit:
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