The L1Md long interspersed repeat family in the mouse: almost all examples are truncated at one end
Open Access
- 20 December 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 11 (24) , 8847-8859
- https://doi.org/10.1093/nar/11.24.8847
Abstract
We have characterized a large repetitive element which has been found at seven different locations within the beta globin locus of the BALB/c mouse. This repeat has an unusual structure in that each of the different members has the same end of the element conserved while the other end terminates at a different point in each repeat member. The sequences within the repeats from the beta globin locus have homology with other repetitive families such as the MIF-1, Bam-5, R, and the BamHl families. These were recently proposed (T. Fanning, (1983) Nucleic Acids Res. 11, 5073–5091) to be part of a structure with the same organization which we found in the globin locus. Probing plaques from a BALB/c genomic library with sequences derived from the repeats in the globin locus shows that virtually all of the repeats from this family are organized in a manner consistent with the proposed structure.Keywords
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